RAD54L2
Domain
Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to be important for the association with nuclear receptors.
Function
DNA helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro (By similarity).
Post-translational modifications
Sumoylated.
Sequence Similarities
Belongs to the SNF2/RAD54 helicase family.
Cellular localization
- Nucleus
- Localizes in speckle-like nuclear compartments.
Alternative names
ARIP4, KIAA0809, RAD54L2, Helicase ARIP4, Androgen receptor-interacting protein 4, RAD54-like protein 2