RADX
Function
Single-stranded DNA-binding protein recruited to replication forks to maintain genome stability (PubMed:28735897). Prevents fork collapse by antagonizing the accumulation of RAD51 at forks to ensure the proper balance of fork remodeling and protection without interfering with the capacity of cells to complete homologous recombination of double-strand breaks (PubMed:28735897).
Cellular localization
- Chromosome
- Recruited to replication forks.
Alternative names
CXorf57, RADX, RPA-related protein RADX