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CHM

OverviewProducts

Function

Acts as a mRNA export factor involved in nucleocytoplasmic transport (PubMed:20498086, PubMed:33849972). Plays a role in mitotic bipolar spindle formation (PubMed:17172455). May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455).

Sequence similarities

Belongs to the WD repeat rae1 family.

Cellular localization

  • Cytoplasm
  • Nucleus
  • Cytoplasm
  • Cytoskeleton
  • Spindle pole
  • Nucleus envelope
  • Recruited from interphase nuclei to spindle MTs during mitosis.

Alternative names

MRNP41, RAE1, mRNA export factor RAE1, Rae1 protein homolog, mRNA-associated protein mrnp 41

Database links

Target type

Proteins

Primary research area

Epigenetics

Molecular weight

40968Da

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