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Ras-GEF domain-containing family member 1A

Function

Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.

Tissue Specificity

Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies.

Alternative names

Ras-GEF domain-containing family member 1A, RASGEF1A

swissprot:Q8N9B8 entrezGene:221002