Ras-related protein Rab-5B

Protein transport. Probably involved in vesicular traffic.

Phosphorylation of Ser-84 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitors GDI1 and GDI2.

(Microbial infection) Glycosylated on arginine residues by S.typhimurium protein Ssek3.

Belongs to the small GTPase superfamily. Rab family.

• Cell membrane
• Lipid-anchor
• Cytoplasmic side
• Early endosome membrane
• Lipid-anchor
• Melanosome
• Enriched in stage I melanosomes.

Ras-related protein Rab-5B, RAB5B

• entrezGene:5869
• omim:179514
• swissprot:P61020

Proteins

Neuroscience

23707Da