RASD1
Function
Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65 (By similarity).
Post-translational modifications
S-nitrosylation stimulates guanine-nucleotide exchange activity.
Sequence Similarities
Belongs to the small GTPase superfamily. RasD family.
Tissue Specificity
Expressed in a variety of tissues including heart, cardiovascular tissues, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, gastrointestinal and reproductive tissues.
Cellular localization
- Cell membrane
- Lipid-anchor
- Cytoplasmic side
- Cytoplasm
- Perinuclear region
- Nucleus
Alternative names
AGS1, DEXRAS1, RASD1, Dexamethasone-induced Ras-related protein 1, Activator of G-protein signaling 1