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RBFOX3
Function
Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
Cellular localization
- Nucleus
- Cytoplasm
- Largely restricted to neuronal nuclei. However, significant cytoplasmic localization in neurons from brains from HIV-infected individuals with cognitive impairment.
Alternative names
- RNA binding protein fox-1 homolog 3
- Fox-1 homolog C
- Neuronal nuclei antigen
- NeuN antigen
- RBFOX3
Database links
Target type
Proteins
Primary research area
Neuroscience
Molecular weight
33873Da