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RBMY1A1

Developmental stage

Expressed in all of the transcriptionally active stages of germ cell development from spermatogonia through spermatocytes to round spermatids.

Function

RNA-binding protein involved in pre-mRNA splicing. Required for sperm development. Acts additively with TRA2B to promote exon 7 inclusion of the survival motor neuron SMN. Binds non-specifically to mRNAs.

Tissue Specificity

Testis-specific.

Cellular localization

Alternative names

RBM1, RBM2, YRRM1, YRRM2, RBMY1A1, RNA-binding motif protein 1, RNA-binding motif protein 2, Y chromosome RNA recognition motif 1, hRBMY

swissprot:P0DJD3 entrezGene:5940 omim:400006