RBP1
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Function
Cytoplasmic retinol-binding protein (PubMed:22665496, PubMed:26900151, PubMed:28057518). Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubMed:22665496).
Sequence Similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Tissue Specificity
Detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver.
Cellular localization
- Cytoplasm
- Lipid droplet
Alternative names
CRBP1, RBP1, Retinol-binding protein 1, Cellular retinol-binding protein, Cellular retinol-binding protein I, CRBP, CRBP-I