RBP5
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Function
Intracellular transport of retinol.
Sequence Similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Tissue Specificity
Higher expression in adult kidney and liver and to a lesser extent in adult and fetal spleen, adult lymph nodes and appendix, and fetal liver and kidney. Strongly decreased in hepatocellular carcinoma tissues (at protein level).
Cellular localization
- Cytoplasm
Alternative names
Retinol-binding protein 5, Cellular retinol-binding protein III, HRBPiso, CRBP-III, RBP5