Regulator of G-protein signaling 5
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity).
Cellular localization
- Isoform 1
- Cytoplasm
- Membrane
- Isoform 2
- Cytoplasm
Alternative names
Regulator of G-protein signaling 5, RGS5