Ren1
Function
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
Sequence Similarities
Belongs to the peptidase A1 family.
Cellular localization
- Secreted
- Membrane
- Associated to membranes via binding to ATP6AP2.
Alternative names
Ren, Ren1, Renin, Angiotensinogenase