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RFX1

Function

Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter.

Sequence Similarities

Belongs to the RFX family.

Cellular localization

Alternative names

MHC class II regulatory factor RFX1, Enhancer factor C, Regulatory factor X 1, Transcription factor RFX1, EF-C, RFX, RFX1

swissprot:P22670 omim:600006 entrezGene:5989