RFX4
Function
Transcription factor that plays a role in early brain development. May activate transcription by interacting directly with the X-box. May activate transcription from CX3CL1 promoter through the X-box during brain development. May be required for neural tube ciliogenesis during embryogenesis (By similarity).
Sequence Similarities
Belongs to the RFX family.
Tissue Specificity
Isoform 1: Expressed in brain and gliomas (at protein level). Isoform 2: Testis-specific (at protein level). Isoform 3: Testis-specific (at protein level). Isoform 3: Expressed at a higher level in adult testes and ejaculated spermatozoa than in fetal testes. Isoform 4: Testis-specific.
Cellular localization
- Nucleus
Alternative names
Transcription factor RFX4, Regulatory factor X 4, Testis development protein NYD-SP10, RFX4