RGP1
Function
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.
Sequence Similarities
Belongs to the RGP1 family.
Cellular localization
- Cytoplasm
- Cytosol
- Membrane
Alternative names
KIAA0258, RGP1, RAB6A-GEF complex partner protein 2, Retrograde Golgi transport protein RGP1 homolog