RHOV
Function
Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway.
Sequence Similarities
Belongs to the small GTPase superfamily. Rho family.
Tissue Specificity
Highly expressed in pancreas, placenta, and fetal brain.
Cellular localization
- Cell membrane
- Lipid-anchor
- Cytoplasmic side
- Endosome membrane
- Lipid-anchor
- Cytoplasmic side
- Treatment with TNF activates endosomal but not plasma membrane RHOV.
Alternative names
ARHV, WRCH2, RHOV, Rho-related GTP-binding protein RhoV, CDC42-like GTPase 2, GTP-binding protein-like 2, Rho GTPase-like protein ARHV, Wnt-1 responsive Cdc42 homolog 2, WRCH-2