Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the 'visual cycle'.
Bothnia retinal dystrophy
BRD
A type of retinitis punctata albescens. Affected individuals show night blindness from early childhood with features consistent with retinitis punctata albescens and macular degeneration.
None
The disease is caused by variants affecting the gene represented in this entry.
Rod-cone dystrophy Newfoundland
NFRCD
A rod-cone dystrophy reminiscent of retinitis punctata albescens but with a substantially lower age at onset and more-rapid and distinctive progression. Rod-cone dystrophies results from initial loss of rod photoreceptors, later followed by cone photoreceptors loss.
None
The disease is caused by variants affecting the gene represented in this entry.
Retinitis punctata albescens
RPA
A form of fleck retina disease characterized by aggregation of white flecks posteriorly in the retina, causing night blindness and delayed dark adaptation. It differs from fundus albipunctatus in being progressive and evolving to generalized atrophy of the retina.
None
The disease is caused by variants affecting the gene represented in this entry.
Retina and pineal gland. Not present in photoreceptor cells but is expressed abundantly in the adjacent retinal pigment epithelium (RPE) and in the Mueller glial cells of the retina.
CRALBP, RLBP1, Retinaldehyde-binding protein 1, Cellular retinaldehyde-binding protein
Proteins
Developmental Biology
36474Da
We found 10 products in 2 categories
ab15051
ab154898
ab199992
ab231967