RLN2

Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

Belongs to the insulin family.

Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary.

• Secreted

Prorelaxin H2, RLN2

• entrezGene:6013
• entrezGene:6019
• omim:179740
• omim:179730
• swissprot:P04090
• swissprot:P04808

Proteins

Cardiovascular

21043Da