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RNQ1

Domain

The prion domain (PrD) is a Gln/Asn (Q/N)-rich domain, which is unstructured in its native, soluble form, and which forms a parallel in-register beta-sheet in its amyloid form.

Function

Transferable epigenetic modifier which forms a prion responsible for the non-Mendelian trait [PIN+]. The native function of the soluble protein is unknown.

Cellular localization

Alternative names

YCL028W, YCL181, YCL28W, RNQ1, [PIN+] prion protein RNQ1, Rich in asparagine and glutamine protein 1

swissprot:P25367 entrezGene:850329