RPL7A
Function
Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:32669547).
Involvement in disease
Chromosomal recombination involving RPL7A activates the receptor kinase domain of the TRK oncogene.
Sequence Similarities
Belongs to the eukaryotic ribosomal protein eL8 family.
Cellular localization
- Cytoplasm
Alternative names
SURF-3, SURF3, RPL7A, Large ribosomal subunit protein eL8, 60S ribosomal protein L7a, PLA-X polypeptide, Surfeit locus protein 3