40S ribosomal protein S20

Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).

Polyubiquitinated by ZNF598 via 'Lys-63'-linked ubiquitin chains when a ribosome has stalled, initiating the ribosome quality control (RQC) pathway to degrade the potentially detrimental aberrant nascent polypeptide (PubMed:28065601, PubMed:28132843, PubMed:28685749, PubMed:32011234, PubMed:36302773). Deubiquitinated by OTUD3 and USP21, antagonizing ZNF598 activity (PubMed:32011234).

Ufmylated by UFL1.

Belongs to the universal ribosomal protein uS10 family.

• Cytoplasm

Small ribosomal subunit protein uS10, 40S ribosomal protein S20, RPS20

• entrezGene:6224
• omim:603682
• swissprot:P60866

Proteins

Metabolism

13373Da