RPS8
Function
Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
Sequence Similarities
Belongs to the eukaryotic ribosomal protein eS8 family.
Cellular localization
- Cytoplasm
- Membrane
- Lipid-anchor
- Nucleus
- Nucleolus
- Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Alternative names
OK/SW-cl.83, RPS8, Small ribosomal subunit protein eS8, 40S ribosomal protein S8