RSL1D1
Function
Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.
Sequence Similarities
Belongs to the universal ribosomal protein uL1 family. Highly divergent.
Tissue Specificity
Expressed at high intensities in the heart, skeletal muscle, and placenta.
Cellular localization
- Nucleus
- Nucleolus
- Colocalizes with ING1 in the nucleolus after UV stress.
Alternative names
CATX11, CSIG, PBK1, L12, RSL1D1, Ribosomal L1 domain-containing protein 1, CATX-11, Cellular senescence-inhibited gene protein, Protein PBK1