Rxrb
Domain
Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
Function
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
Sequence Similarities
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Tissue Specificity
In all tissues tested, including brain, thymus, spleen and liver.
Cellular localization
- Nucleus
- Cytoplasm
Alternative names
Nr2b2, Retinoic acid receptor RXR-beta, MHC class I regulatory element-binding protein H-2RIIBP, Nuclear receptor subfamily 2 group B member 2, Retinoid X receptor beta