S-methylmethionine--homocysteine S-methyltransferase BHMT2
Function
Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor.
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (BhmT route): step 1/1.
Tissue Specificity
Expressed in liver and kidney and at reduced levels in the brain, heart, and skeletal muscle.
Alternative names
S-methylmethionine--homocysteine S-methyltransferase BHMT2, SMM-hcy methyltransferase, Betaine--homocysteine S-methyltransferase 2, BHMT2