S100A2
Developmental stage
Preferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived ones. The level of S100L was shown to correlate inversely with tumor progression.
Function
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth.
Sequence Similarities
Belongs to the S-100 family.
Tissue Specificity
A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.
Alternative names
S100L, S100A2, Protein S100-A2, CAN19, Protein S-100L, S100 calcium-binding protein A2