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Function

Major acute phase reactant. Apolipoprotein of the HDL complex.

Involvement in disease

Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.

Post-translational modifications

This protein is the precursor of amyloid protein A, which is formed by the removal of residues from the C-terminal end.

Sequence similarities

Belongs to the SAA family.

Tissue specificity

Expressed by the liver; secreted in plasma.

Cellular localization

  • Secreted

Alternative names

Serum amyloid A protein, SAA, SAA1

Target type

Proteins

Primary research area

Immuno-oncology

Molecular weight

14339Da

We found 2 products in 2 categories

Assay Kits

Target

Reactive species

Detection method

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'SAA1' (2)

Products