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Function

Major acute phase reactant. Apolipoprotein of the HDL complex.

Involvement in disease

Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.

Post-translational modifications

This protein is the precursor of amyloid protein A, which is formed by the removal of residues from the C-terminal end.

Sequence similarities

Belongs to the SAA family.

Tissue specificity

Expressed by the liver; secreted in plasma.

Cellular localization

  • Secreted

Alternative names

SAA, SAA1, Serum amyloid A protein

Target type

Proteins

Primary research area

Immuno-oncology

We found 1 product in 1 category

Assay Kits

Target

Reactive species

Detection method

Search our catalogue for 'SAA1' (1)

Products