SAFB2
Function
Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
Tissue Specificity
Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
Cellular localization
- Cytoplasm
- Nucleus
Alternative names
KIAA0138, SAFB2, Scaffold attachment factor B2, SAF-B2