Mitochondrial DNA endonuclease involved in intron homing. It introduces a specific double-strand break in the DNA of the 21S rRNA gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Specifically recognizes and cleaves the sequence 5'-TAGGGATAACAGGGTAAT-3'.
Belongs to the LAGLIDADG endonuclease family.
OMEGA, SECY, Q0160, SCEI, Intron-encoded endonuclease I-SceI, 21S rRNA intron maturase, Homing endonuclease omega
Proteins
27683Da
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