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SCGB3A1

Function

Secreted cytokine-like protein. Inhibits cell growth in vitro.

Sequence Similarities

Belongs to the secretoglobin family. UGRP subfamily.

Tissue Specificity

Highly expressed in lung and prostate (PubMed:11481438). Also found in mammary gland, spleen, pancreas, testis and liver (PubMed:11481438). Detected throughout the airway epithelium in lung, with highest expression in large airways (PubMed:12406855). Found in lung submucosal glands where it localizes to acinar and ductile cells (PubMed:12406855). Not detected in respiratory bronchioles, alveolar ducts or alveolar epithelium (PubMed:12406855). In mammary gland, specifically localizes to luminal epithelial cells (PubMed:11481438).

Cellular localization

Alternative names

HIN1, PNSP2, UGRP2, UNQ629/PRO1245, SCGB3A1, Secretoglobin family 3A member 1, Cytokine HIN-1, High in normal 1, Pneumo secretory protein 2, Uteroglobin-related protein 2, PnSP-2

swissprot:Q96QR1 entrezGene:92304 omim:606500