SDF4
Domain
Binds calcium via its EF-hands (By similarity). Isoform 5 binds calcium.
Function
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.
Sequence Similarities
Belongs to the CREC family.
Tissue Specificity
Ubiquitous. Isoform 5 is expressed in pancreas.
Cellular localization
- Isoform 1
- Golgi apparatus lumen
- Isoform 5
- Cytoplasm
- Cell membrane
- Cell projection
- Bleb
- Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.
Alternative names
CAB45, PSEC0034, SDF4, 45 kDa calcium-binding protein, Cab45, Stromal cell-derived factor 4, SDF-4