SEC23IP
Function
Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P).
Sequence Similarities
Belongs to the PA-PLA1 family.
Tissue Specificity
Ubiquitously expressed with stronger levels detected in heart, liver and skeletal muscle.
Cellular localization
- Cytoplasmic vesicle
- COPII-coated vesicle membrane
- Peripheral membrane protein
- Cytoplasmic side
- Endoplasmic reticulum
Alternative names
MSTP053, SEC23IP, SEC23-interacting protein, p125