Sele

Function

Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.

Sequence similarities

Belongs to the selectin/LECAM family.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

• ELAM1
• SELE
• ELAM1
• E-selectin
• CD62 antigen-like family member E
• Endothelial leukocyte adhesion molecule 1
• Leukocyte-endothelial cell adhesion molecule 2
• ELAM-1
• LECAM2

Database links

• entrezGene:6401
• omim:131210
• swissprot:P16581

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

66655Da