Sell

Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia (PubMed:12403782, PubMed:28011641).

N-glycosylated.

Belongs to the selectin/LECAM family.

Expressed in B-cell lines and T-lymphocytes.

• Cell membrane
• Single-pass type I membrane protein

CD62L, LNHR, LYAM1, SELL, L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, TQ1, gp90-MEL, LAM-1, LECAM1

• entrezGene:6402
• omim:153240
• swissprot:P14151

Proteins

Immunology & Infectious Disease

• Immuno-oncology

42187Da