Sell

Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes (PubMed:1693096). Promotes initial tethering and rolling of leukocytes in endothelia (By similarity).

N-glycosylated.

Belongs to the selectin/LECAM family.

Predominantly expressed in lymphoid tissue.

• Cell membrane
• Single-pass type I membrane protein

CD62L, Lnhr, Ly-22, Ly22, Sell, L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, Leukocyte-endothelial cell adhesion molecule 1, Lymph node homing receptor, Lymphocyte antigen 22, Lymphocyte surface MEL-14 antigen, LAM-1, LECAM1

• entrezGene:20343
• swissprot:P18337

Proteins

Immunology & Infectious Disease

• Immuno-oncology

42288Da