SEMA3D
Domain
Strong binding to neuropilin is mediated by the carboxy third of the protein.
Function
Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin (By similarity).
Sequence Similarities
Belongs to the semaphorin family.
Cellular localization
- Secreted
Alternative names
UNQ760/PRO1491, SEMA3D, Semaphorin-3D