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SEPHS2

Function

Synthesizes selenophosphate from selenide and ATP.

Post-translational modifications

Truncated SEPHS2 proteins produced by failed UGA/Sec decoding are ubiquitinated by the CRL2(KLHDC3) complex, which recognizes the glycine (Gly) at the C-terminus of truncated SEPHS2 proteins.

Sequence Similarities

Belongs to the selenophosphate synthase 1 family. Class I subfamily.

Alternative names

SPS2, SEPHS2, Selenium donor protein 2, Selenophosphate synthase 2

swissprot:Q99611 entrezGene:22928 omim:606218