Serpina10
Function
Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors (By similarity).
Post-translational modifications
Phosphorylated by FAM20C in the extracellular medium.
Sequence Similarities
Belongs to the serpin family.
Tissue Specificity
Detectable in liver, but not in heart, brain, spleen, lung, kidney, skeletal muscle or testes.
Cellular localization
- Secreted
Alternative names
Zpi, Serpina10, Protein Z-dependent protease inhibitor, PZ-dependent protease inhibitor, PZI, Serpin A10