Serpina6
Domain
Proteolytic cleavage leads to an important conformation change. This reduces the affinity for steroids (By similarity).
Function
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Sequence Similarities
Belongs to the serpin family.
Tissue Specificity
Expressed by the liver; secreted in plasma.
Cellular localization
- Secreted
Alternative names
Cbg, Serpina6, Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin