SERPINA9
Function
Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).
Sequence Similarities
Belongs to the serpin family.
Tissue Specificity
Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies.
Cellular localization
- Isoform 1
- Secreted
- Isoform 2
- Cytoplasm
- Isoform 3
- Cytoplasm
- Isoform 4
- Cytoplasm
- Isoform 5
- Cytoplasm
- Isoform 6
- Cytoplasm
- Isoform 7
- Membrane
- Single-pass type II membrane protein
Alternative names
GCET1, SERPINA11, UNQ692/PRO1337, SERPINA9, Serpin A9, Centerin, Germinal center B-cell-expressed transcript 1 protein