Serpine2
Function
Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
Sequence Similarities
Belongs to the serpin family.
Tissue Specificity
Most abundant in seminal vesicles.
Cellular localization
- Secreted
- Extracellular space
Alternative names
Pi7, Pn1, Spi4, Serpine2, Glia-derived nexin, GDN, Peptidase inhibitor 7, Protease nexin 1, Protease nexin I, Serine protease-inhibitor 4, Serpin E2, PI-7, PN-1