The FZ domain is involved in binding with Wnt ligands.
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Belongs to the secreted frizzled-related protein (sFRP) family.
Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Proteins
Oncology
33490Da
We found 4 products in 1 category
ab137560
ab92667