SFXN5
Function
Mitochondrial amino-acid transporter (By similarity). Transports citrate (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity) (PubMed:30442778). In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (By similarity).
Sequence Similarities
Belongs to the sideroflexin family.
Tissue Specificity
Primarily expressed in the brain.
Cellular localization
- Mitochondrion inner membrane
- Multi-pass membrane protein
Alternative names
Sideroflexin-5, SFXN5