Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Muscular dystrophy, limb-girdle, autosomal recessive 6
LGMDR6
An autosomal recessive degenerative myopathy initially affecting the proximal limb girdle musculature. Muscle from patients shows a complete loss of delta-sarcoglycan as well as of the others components of the sarcoglycan complex.
None
The disease is caused by variants affecting the gene represented in this entry.
Cardiomyopathy, dilated 1L
CMD1L
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
None
The disease is caused by variants affecting the gene represented in this entry.
Glycosylated.
Disulfide bonds are present.
Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
Proteins
32071Da
We found 5 products in 2 categories
ab240108
Anti-delta Sarcoglycan antibody [EPR8706] - BSA and Azide free
ab115019