Skip to main content

SHOX2

Developmental stage

Expressed during cranofacial development as well as in heart.

Function

May be a growth regulator and have a role in specifying neural systems involved in processing somatosensory information, as well as in face and body structure formation.

Sequence similarities

Belongs to the paired homeobox family. Bicoid subfamily.

Tissue specificity

Expressed in heart, skeletal muscle, liver, lung, bone marrow fibroblast, pancreas and placenta.

Cellular localization

  • Nucleus

Alternative names

  • Short stature homeobox protein 2
  • Homeobox protein Og12X
  • Paired-related homeobox protein SHOT
  • SHOT
  • OG12X
  • SHOX2

Target type

Proteins

Molecular weight

34953Da