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Function

Binds sialylated glycoproteins.

Sequence similarities

Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Tissue specificity

Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.

Cellular localization

  • Membrane
  • Single-pass type I membrane protein

Alternative names

CD33L3, SIGLEC15, Sialic acid-binding Ig-like lectin 15, Siglec-15, CD33 antigen-like 3

Target type

Proteins

Primary research area

Immuno-oncology

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