Signal recognition particle 19 kDa protein
Function
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity). Binds directly to 7SL RNA (By similarity). Mediates binding of SRP54 to the SRP complex (By similarity).
Sequence Similarities
Belongs to the SRP19 family.
Cellular localization
- Cytoplasm
- Nucleus
- Nucleolus
- Nucleus
- Nucleoplasm
- Although the signal recognition particle complex acts in the cytoplasm, it assembles at least in part in the nucleus and/or the nucleolus. SRP19 nuclear import may be mediated by IPO8/Imp8 and TPNO1/Trn.
Alternative names
Signal recognition particle 19 kDa protein, SRP19