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SLC18A2
Function
Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis (By similarity).
Sequence similarities
Belongs to the major facilitator superfamily. Vesicular transporter family.
Cellular localization
- Cytoplasmic vesicle membrane
- Multi-pass membrane protein
Alternative names
- Synaptic vesicular amine transporter
- Monoamine transporter
- Solute carrier family 18 member 2
- Vesicular amine transporter 2
- VAT2
- Vmat2
- Slc18a2
Database links
Target type
Proteins
Primary research area
Neuroscience
Molecular weight
55754Da