SLC25A51

Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria (PubMed:32906142, PubMed:33087354, PubMed:33262325). Mitochondrial NAD(+) is required for glycolysis and mitochondrial respiration (PubMed:32906142, PubMed:33087354, PubMed:33262325). Compared to SLC25A52, SLC25A51-mediated transport is essential for the import of NAD(+) in mitochondria (PubMed:32906142). The transport mechanism, uniport or antiport, its electrogenicity and substrate selectivity, remain to be elucidated.

Belongs to the mitochondrial carrier (TC 2.A.29) family.

• Mitochondrion inner membrane
• Multi-pass membrane protein

MCART1, SLC25A51, Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51, Mitochondrial NAD(+) transporter SLC25A51, Mitochondrial carrier triple repeat protein 1, Solute carrier family 25 member 51

• entrezGene:92014
• swissprot:Q9H1U9

Proteins

Immunology & Infectious Disease

33672Da